GMP, GCP & Quality Control

Biography

Biography: Raja Chakaverty

Abstract

In this presentation, the focus will be on systematically discussing the methods adopted and their application in quality control and standardization of herbal drugs. For this purpose a comprehensive literature review was performed on recent articles related to the core theme of the presentation from the current bibliographic, abstracting and indexing services including PubMed. It is a fact that herbal medicines of a kind planted or in the wild usually differ from each other greatly based on their storage under different environmental conditions. Even the quality parameters of the same batch of herbal medicine may vary significantly. Therefore, it is of utmost significance to ensure the quality of herbal medicines through effective and convenient analytical methods. The quality control of herbal medicines generally involves three steps. The first is false and true identification, the second is to distinguish originating regions of herbs, and the third is quality evaluation. The false and true identification aims to distinguish the species by means of many qualitative analytical methods. The qualities of herbs are closely related to their producing areas. For this reason, the determination of producing regions is critical. The quality of herbs depends on the environments, collecting time of these products and the storage conditions. The quality control analytical techniques have undergone a paradigm shift of sorts since in the recent years transcending from the typical estimates from the morphology, microscopic feature identifications to the physical and chemical properties based on the major constituent identification to almost all components being identification based on utilization of the fingerprint spectra and allied chromatographic techniques.